ADDGENE links to new DREADDs

AAV packaging vector for CamKIIa driven KOR DREADD expression

Comments

  1. Are there other mCitrine based variants of DREADDs such as AAV-hSyn-DIO-hm3D(Gq)-mcitrine available and validated?

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  2. We recently performed a control experiment using this virus without Cre to check for any possible spurious expression. Surprisingly, there was considerable mCitrine but no HA expression. How is it possible that there is significant mCitrine expression without Cre? Why is mCitrine expressed and no HA? Does this mean the KORD itself is being expressed without the Cre recombinase too?
    Thanks for your help!

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