Posts

CNO via minipump (Science paper, Moser labs)

I often get questions regarding CNO via minipump and here is a nice example where that seems to work.

DREADDs and OPTO modulating VTA terminals

Dopamine terminals from the ventral tegmental area gate intrinsic inhibition in the prefrontal cortex

DREADD-modulation of 5HT neurons causes perseverative responding

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Activity patterns of serotonin neurons underlying cognitive flexibility

DREADDing proglucagon neurons

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Nice commentary here at JCI

Nice use of DREADDs to dissect GPCR signaling underlying anxiety

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Great bit of work by Kash lab and many others using Gi, Gs and Gq =DREADDs to deconstruct pathways essential for anxiety in BNST

INTERSECTIONAL RETRO-DREADD

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Interesting paper here :

Nature communications: Rescuing social behavioral deficits with DREADDs

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Paper here