DREADD users blog

Now on-line at Neuron . The constructs will be available soon from ADDGENE   without MTA. Viruses will be available next week (May 3) from UNC . This DREADD is activated by salvinorin B which may be purchased from Cayman  or from S cott Wyer at Apple Pharms at a great discount.

Interesting paper in Cell Reports on this topic.

Astrocytes Control Food Intake by Inhibiting AGRP Neuron Activity via Adenosine A 1  Receptors

Here is a paper just published which provides for an open-source resource for screening the druggable human GPCR-ome for off-target actions of chemogenetic chemical actuators.  The cDNAs will soon be available from ADDGENE and are available until then from the Roth lab.

A cool paper using this technology to deconstruct Neuronal ensembles sufficient for recovery sleep and the sedative actions of α 2  adrenergic agonists

Nice paper in PNAS by Caron's lab.