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Showing posts from July, 2016

DREADDSs demonstrate glutamatergic class of neurons in the brainstem and spinal cord, the V2a class, drives increased respiratory activity

Using a chemogenetic approach, we demonstrate that a glutamatergic class of neurons in the brainstem and spinal cord, the V2a class, is sufficient to drive increased ARM activity at rest in healthy mice.

How to find all publications related to DREADD technology

Simply go to Google Scholar and type in the following:

"designer receptors exclusively" OR DREADD OR hM3D OR hM4D

DREADDs in primate amygdala

Been hearing about this for some time now it is published

DREADDs suppress seizures in mouse model of pharmacoresistant epilepsy

Video primer of DREADDs in primates

Link at YouTube

Combining opto/DREADD to deconstruct medial amygdala regulation of social dynamics

interesting and comprehensive paper here.

Chemogenetic silencing of the midline and intralaminar thalamus blocks amygdala-kindled seizures

cool paper here of potential translational impact

Use of DREADDs to Dissect Metabolic Pathways

Nice review by Jurgen Wess here

Impaired Recall of Positional Memory following Chemogenetic Disruption of Place Field Stability

Nice use of ivermectin-actuated channels for silencing neurons and dissecting behavior.