Showing posts from October, 2014

Happy Halloween from the Roth lab


Manipulating a cocaine 'engram' chemogenetically

Pretty amazing paper now on-line from the Josselyn/Frankland labs showing that

"...Ablating or silencing neurons overexpressing CREB (due to cocaine) before testing disrupted the expression of a previously acquired cocaine memory, suggesting ... a critical hub in what is likely a larger cocaine memory engram."

DREADD review now on-line

A comprehensive review with many useful tables of DREADD applications is now on-line.

Floxed DREADD mice

I get many requests for these.

The Rothlab may have such beasts in hand and will make them available via JAX as soon as they are validated. Rather than sending emails to that lab directly, as soon as the mice are deposited in JAX it will be announced here.