Manipulating a cocaine 'engram' chemogenetically
Pretty amazing paper now on-line from the Josselyn/Frankland labs showing that
"...Ablating or silencing neurons overexpressing CREB (due to cocaine) before testing disrupted the expression of a previously acquired cocaine memory, suggesting ... a critical hub in what is likely a larger cocaine memory engram."
"...Ablating or silencing neurons overexpressing CREB (due to cocaine) before testing disrupted the expression of a previously acquired cocaine memory, suggesting ... a critical hub in what is likely a larger cocaine memory engram."
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