DREADD users blog

A quite amazing paper has appeared recently here. Of note is the replication of a technology reported previously of DREADD-assisted neuronal activity mapping.

Interesting paper from the Linda Buck lab now on-line .

Nice paper just published . Key data below:

Another paper showing the utility of both RETRO-DREADD and KOR-DREADD technology.

Pretty interesting paper published a couple of weeks back in Cell ; key data below:

From an eLife paper  where DREADDs were used extensively: " For hM4D(Gi) experiments, we infected V1 of P30-60 PV-Cre mice or wild-type littermates with an AAV9-hSyn-DIO-HA-hM4D(Gi)-IRES-mCitrine virus (UNC viral core – generated by Dr. Brian Roth’s laboratory)" There are plenty of Brian and Bryan out there and here is a photo of 3 at once (Bryan Roth, Brian Kobilka [Nobel 2012], Brian Shoichet)

Nice paper here using Gq-DREADD and many other approaches to deconstruct Gq signaling in various adipose tissues.

Interesting paper in Nature Neuroscience . Data below:

Paper here.