DREADDs in 2015

In 2015 there were 358 papers where DREADD technology played an important role.  I created a WORDLE using these and it looks like (no surprise) Neurons were used as frequent targets.

My top picks for 2015:

1. Chemogenetic disconnection of monkey orbitofrontal and rhinal cortex reversibly disrupts reward value.
Eldridge MA, Lerchner W, Saunders RC, Kaneko H, Krausz KW, Gonzalez FJ, Ji B, Higuchi M, Minamimoto T, Richmond BJ.
Nat Neurosci. 2016 Jan;19(1):37-9. doi: 10.1038/nn.4192. Epub 2015 Dec 14.

2.  A New DREADD Facilitates the Multiplexed Chemogenetic Interrogation of Behavior.
Vardy E, Robinson JE, Li C, Olsen RH, DiBerto JF, Giguere PM, Sassano FM, Huang XP, Zhu H, Urban DJ, White KL, Rittiner JE, Crowley NA, Pleil KE, Mazzone CM, Mosier PD, Song J, Kash TL, Malanga CJ, Krashes MJ, Roth BL.
Neuron. 2015 May 20;86(4):936-46. doi: 10.1016/j.neuron.2015.03.065. Epub 2015 Apr 30

3.  The first structure-activity relationship studies for designer receptors exclusively activated bydesigner drugs.
Chen X, Choo H, Huang XP, Yang X, Stone O, Roth BL, Jin J.
ACS Chem Neurosci. 2015 Mar 18;6(3):476-84. doi: 10.1021/cn500325v. Epub 2015 Jan 27




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