PNAS: visualization of in vivo silencing via hM4Di

Frequently am asked whether anyone has actually seen neurons 'silenced in vivo' via hM4Di.

Here is the relevant data from a paper just out in PNAS.  It shows a great example of how chemogenetics can provide the killer experiment when linked with in vivo neuronal imaging of neuronal activity.


Comments

Popular posts from this blog

Update on AAVs for DREADDs