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Showing posts from July, 2016

DREADDSs demonstrate glutamatergic class of neurons in the brainstem and spinal cord, the V2a class, drives increased respiratory activity

 Using a chemogenetic approach, we demonstrate that a glutamatergic class of neurons in the brainstem and spinal cord, the V2a class, is sufficient to drive increased ARM activity at rest in healthy mice.
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How to find all publications related to DREADD technology

Simply go to Google Scholar and type in the following: "designer receptors exclusively" OR DREADD OR hM3D OR hM4D
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DREADDs in primate amygdala

Been hearing about this for some time now it is published
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DREADDs suppress seizures in mouse model of pharmacoresistant epilepsy

Paper here
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Video primer of DREADDs in primates

Link at YouTube
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Combining opto/DREADD to deconstruct medial amygdala regulation of social dynamics

interesting and comprehensive paper here.
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Chemogenetic silencing of the midline and intralaminar thalamus blocks amygdala-kindled seizures

cool paper here of potential translational impact
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Use of DREADDs to Dissect Metabolic Pathways

Nice review by Jurgen Wess here
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Impaired Recall of Positional Memory following Chemogenetic Disruption of Place Field Stability

Nice use of ivermectin-actuated channels f or silencing neurons and dissecting behavior.
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