Nice use of DREADDs to dissect GPCR signaling underlying anxiety
Great bit of work by Kash lab and many others using Gi, Gs and Gq =DREADDs to deconstruct pathways essential for anxiety in BNST
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INTERSECTIONAL RETRO-DREADD
Update on AAVs for DREADDs
UNC is no longer offering single-unit AAV for DREADDs although we expect that these will be available via ADDGENE shortly.
To get onto the ADDGENE notification list contact: Leila Haery haery@addgene.org with serotype and genotype needs for DREADD constructs. She will be helping Addgene coordinate production and distribution of DREADD viruses.
In the meantime, you can order plasmids from ADDGENE and simply ask UNC to make a custom prep for you or send the plasmids to the Penn Vector core.
Alternatively it looks like the Duke vector core is also offering DREADD-based AAVs.
Bryan
To get onto the ADDGENE notification list contact: Leila Haery haery@addgene.org with serotype and genotype needs for DREADD constructs. She will be helping Addgene coordinate production and distribution of DREADD viruses.
In the meantime, you can order plasmids from ADDGENE and simply ask UNC to make a custom prep for you or send the plasmids to the Penn Vector core.
Alternatively it looks like the Duke vector core is also offering DREADD-based AAVs.
Bryan
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