Question re: retrograde transport of AAV serotypes

A user asks:

" Publications indicate that AAV5 has a preferential retrograde transport among AAV types. Have you had this same experience?"

A:  My lab has no experience.

There are, though, several recent papers which have looked into this in mouse brain where AAV5 was retrogradely transported, in rat cortical neurons in culture,  in non-human primate where AAV6 is reported to be retrogradely transported, as well as AAV6 in rats appears to be retrogradely transported.

Others with experience are welcome to add comments and/or advice.



Post a Comment

Popular posts from this blog

How best to dissolve CNO depends on what it is soluble in (and that depends on the particular polymorph)