DREADDs using cell-type specific promotors
Q: "Do you know of anyone who has put DREADD into locus coeruleus?"
A: yes a very nice paper recently using PRSx8 and lentivirus. Per the authors:
"PRSx8 is based on an upstream regulatory site in the human DBH promoter and drives high levels of expression in adrenergic neurons"
A: yes a very nice paper recently using PRSx8 and lentivirus. Per the authors:
"PRSx8 is based on an upstream regulatory site in the human DBH promoter and drives high levels of expression in adrenergic neurons"
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