DREADDs define Cortical Feedback Which Regulates Feedforward Retinogeniculate Refinement

Paper here

Comments

  1. Hi,
    We have been ordering DREADDs from the UNC vector core but today while trying to order we found that the Roth lab viruses have disappeared from there? Is this a bug? OR is there a new place to order them from? Thanks a lot!

    Best,
    Arghya
    Caroni Group,
    Friedrich miescher Institute, CH

    ReplyDelete
    Replies
    1. The viral core can make custom preps but you need to get the plasmid from ADDGENE and send it to them. Addgene will soon be providing AAV stocks as well.

      Delete
    2. Thank you for the information!

      Best,
      Arghya

      Delete
    3. Dear Prof Roth,

      Our group is also using DREADDs and we were wondering how soon will these be available as AAV stocks from ADDGENE?

      Many thanks,
      Sanziana,
      University of Oxford

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    4. Hopefully soon. Check back often

      Delete
  2. Dear Prof Roth,
    May I know after iv or ip CNO administration, what time does it block/activate Dreadd to maximum level and how long does it stay at the plateau.
    Best regards
    Irfan

    ReplyDelete

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